3d Printing Of A Personalized Dosage Form
Virtanen, Valtteri Topias
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Personoidun lääkkeen 3D-tulostus
The purpose of this thesis was to study the possibilities of 3D printing of a personalized dosage form from biocompatible and biodegradable PLA (polylactic acid) polymer. In this thesis multiple sets of capsules with different settings were designed and printed with a 3D printer. The chosen designs and printed capsules were evaluated first with leakage tests with a blue dye and then with release tests with Nadolol-nanocellulose mixture. 3D printing turned out to be effective with fast prototyping. The release tests showed that a dosage form printed from PLA polymer with a wine bottle shaped inner cavity provides a stable release profile during long time tests. This can be utilized as a 3D printed personalized implantation device.